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native human igg2 protein  (Abcam)

 
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    Abcam native human igg2 protein
    The total spike-specific <t>IgG</t> and the total serum IgG levels in vaccinated and COVID-19 cohorts. Total spike-specific IgG levels were quantified by in-house ELISA, normalized to positive and negative serum samples ( a ). Total serum IgG levels were measured by nephelometry ( b ). Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort, while red circles represent the COVID-19 cohort. The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG by Siemens Healthcare Diagnostics Inc. The Kruskal–Wallis test followed by Dunn’s multiple comparisons test is presented for the vaccinated cohort. p < 0.05 was considered statistically significant.
    Native Human Igg2 Protein, supplied by Abcam, used in various techniques. Bioz Stars score: 97/100, based on 1415 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/native human igg2 protein/product/Abcam
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    native human igg2 protein - by Bioz Stars, 2026-02
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    Images

    1) Product Images from "Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history"

    Article Title: Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history

    Journal: Scientific Reports

    doi: 10.1038/s41598-023-40103-x

    The total spike-specific IgG and the total serum IgG levels in vaccinated and COVID-19 cohorts. Total spike-specific IgG levels were quantified by in-house ELISA, normalized to positive and negative serum samples ( a ). Total serum IgG levels were measured by nephelometry ( b ). Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort, while red circles represent the COVID-19 cohort. The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG by Siemens Healthcare Diagnostics Inc. The Kruskal–Wallis test followed by Dunn’s multiple comparisons test is presented for the vaccinated cohort. p < 0.05 was considered statistically significant.
    Figure Legend Snippet: The total spike-specific IgG and the total serum IgG levels in vaccinated and COVID-19 cohorts. Total spike-specific IgG levels were quantified by in-house ELISA, normalized to positive and negative serum samples ( a ). Total serum IgG levels were measured by nephelometry ( b ). Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort, while red circles represent the COVID-19 cohort. The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG by Siemens Healthcare Diagnostics Inc. The Kruskal–Wallis test followed by Dunn’s multiple comparisons test is presented for the vaccinated cohort. p < 0.05 was considered statistically significant.

    Techniques Used: Enzyme-linked Immunosorbent Assay, Plasmid Preparation

    The spike-specific, the total serum IgG subclasses and the proportions of each spike-specific IgG subclass to their total serum IgG antibody subclass in the vaccinated ( a ) and the COVID-19 ( b ) cohorts. Levels of spike-specific IgG subclasses were quantified by in-house ELISA calibrated with purified human IgG 1, 2, 3 and 4 antibodies. Total serum IgG subclass concentrations were measured by nephelometry. Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort ( a ), while red circles represent the COVID-19 cohort ( b ). The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG subclass levels by Siemens Healthcare Diagnostics Inc. The values of the Kruskal–Wallis test followed by Dunn’s multiple comparisons test are presented in the vaccinated cohort. p < 0.05 was considered statistically significant.
    Figure Legend Snippet: The spike-specific, the total serum IgG subclasses and the proportions of each spike-specific IgG subclass to their total serum IgG antibody subclass in the vaccinated ( a ) and the COVID-19 ( b ) cohorts. Levels of spike-specific IgG subclasses were quantified by in-house ELISA calibrated with purified human IgG 1, 2, 3 and 4 antibodies. Total serum IgG subclass concentrations were measured by nephelometry. Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort ( a ), while red circles represent the COVID-19 cohort ( b ). The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG subclass levels by Siemens Healthcare Diagnostics Inc. The values of the Kruskal–Wallis test followed by Dunn’s multiple comparisons test are presented in the vaccinated cohort. p < 0.05 was considered statistically significant.

    Techniques Used: Enzyme-linked Immunosorbent Assay, Purification, Plasmid Preparation

    Heatmaps representing the log mean fold change values of spike-specific and total serum IgG subclasses in three follow-up mRNA vaccinated groups between two sampling time points after booster vaccination. The fold changes of spike-specific and total serum IgG subclasses and the proportions of each spike-specific to total serum IgG levels were visualized in heatmaps by the logarithmic values of mean ratios between the second and the first sampling time points. Decreasing trends are shown between 0 and (− 1) and increasing trends were plotted between 0 and 1. The constant level (no change) is indicated as 0.
    Figure Legend Snippet: Heatmaps representing the log mean fold change values of spike-specific and total serum IgG subclasses in three follow-up mRNA vaccinated groups between two sampling time points after booster vaccination. The fold changes of spike-specific and total serum IgG subclasses and the proportions of each spike-specific to total serum IgG levels were visualized in heatmaps by the logarithmic values of mean ratios between the second and the first sampling time points. Decreasing trends are shown between 0 and (− 1) and increasing trends were plotted between 0 and 1. The constant level (no change) is indicated as 0.

    Techniques Used: Sampling

    Contribution of each spike-specific IgG subclass to the sum of all spike-specific IgG antibody levels. The percentages of each spike-specific IgG subclass relative to the sum of spike-specific IgG levels are shown for the vaccinated and COVID-19 cohorts. The numbers represent the mean percentages of individuals calculated by dividing each spike specific IgG levels with the sum of all spike specific IgG levels. Schematic representation of spike-specific IgG1%, IgG2%, IgG3% and IgG4% are shown in blue, orange, grey and yellow sectors, respectively. The size of the pie charts indicates the levels of all spike-specific IgG antibodies from Fig. .
    Figure Legend Snippet: Contribution of each spike-specific IgG subclass to the sum of all spike-specific IgG antibody levels. The percentages of each spike-specific IgG subclass relative to the sum of spike-specific IgG levels are shown for the vaccinated and COVID-19 cohorts. The numbers represent the mean percentages of individuals calculated by dividing each spike specific IgG levels with the sum of all spike specific IgG levels. Schematic representation of spike-specific IgG1%, IgG2%, IgG3% and IgG4% are shown in blue, orange, grey and yellow sectors, respectively. The size of the pie charts indicates the levels of all spike-specific IgG antibodies from Fig. .

    Techniques Used:

    Key resources.
    Figure Legend Snippet: Key resources.

    Techniques Used: Recombinant, Software



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    native human igg2 protein  (Abcam)
    97
    Abcam native human igg2 protein
    The total spike-specific <t>IgG</t> and the total serum IgG levels in vaccinated and COVID-19 cohorts. Total spike-specific IgG levels were quantified by in-house ELISA, normalized to positive and negative serum samples ( a ). Total serum IgG levels were measured by nephelometry ( b ). Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort, while red circles represent the COVID-19 cohort. The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG by Siemens Healthcare Diagnostics Inc. The Kruskal–Wallis test followed by Dunn’s multiple comparisons test is presented for the vaccinated cohort. p < 0.05 was considered statistically significant.
    Native Human Igg2 Protein, supplied by Abcam, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/native human igg2 protein/product/Abcam
    Average 97 stars, based on 1 article reviews
    native human igg2 protein - by Bioz Stars, 2026-02
    97/100 stars
    		  Buy from Supplier

    Image Search Results


    The total spike-specific IgG and the total serum IgG levels in vaccinated and COVID-19 cohorts. Total spike-specific IgG levels were quantified by in-house ELISA, normalized to positive and negative serum samples ( a ). Total serum IgG levels were measured by nephelometry ( b ). Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort, while red circles represent the COVID-19 cohort. The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG by Siemens Healthcare Diagnostics Inc. The Kruskal–Wallis test followed by Dunn’s multiple comparisons test is presented for the vaccinated cohort. p < 0.05 was considered statistically significant.

    Journal: Scientific Reports

    Article Title: Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history

    doi: 10.1038/s41598-023-40103-x

    Figure Lengend Snippet: The total spike-specific IgG and the total serum IgG levels in vaccinated and COVID-19 cohorts. Total spike-specific IgG levels were quantified by in-house ELISA, normalized to positive and negative serum samples ( a ). Total serum IgG levels were measured by nephelometry ( b ). Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort, while red circles represent the COVID-19 cohort. The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG by Siemens Healthcare Diagnostics Inc. The Kruskal–Wallis test followed by Dunn’s multiple comparisons test is presented for the vaccinated cohort. p < 0.05 was considered statistically significant.

    Article Snippet: Native human IgG2 protein , abcam , ab90284.

    Techniques: Enzyme-linked Immunosorbent Assay, Plasmid Preparation

    The spike-specific, the total serum IgG subclasses and the proportions of each spike-specific IgG subclass to their total serum IgG antibody subclass in the vaccinated ( a ) and the COVID-19 ( b ) cohorts. Levels of spike-specific IgG subclasses were quantified by in-house ELISA calibrated with purified human IgG 1, 2, 3 and 4 antibodies. Total serum IgG subclass concentrations were measured by nephelometry. Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort ( a ), while red circles represent the COVID-19 cohort ( b ). The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG subclass levels by Siemens Healthcare Diagnostics Inc. The values of the Kruskal–Wallis test followed by Dunn’s multiple comparisons test are presented in the vaccinated cohort. p < 0.05 was considered statistically significant.

    Journal: Scientific Reports

    Article Title: Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history

    doi: 10.1038/s41598-023-40103-x

    Figure Lengend Snippet: The spike-specific, the total serum IgG subclasses and the proportions of each spike-specific IgG subclass to their total serum IgG antibody subclass in the vaccinated ( a ) and the COVID-19 ( b ) cohorts. Levels of spike-specific IgG subclasses were quantified by in-house ELISA calibrated with purified human IgG 1, 2, 3 and 4 antibodies. Total serum IgG subclass concentrations were measured by nephelometry. Black and blue circles indicate mRNA and vector-vaccinated volunteers in the vaccinated cohort ( a ), while red circles represent the COVID-19 cohort ( b ). The horizontal solid lines indicate group medians, and the horizontal dashed lines indicate 25–75% percentiles. The dotted lines represent the reference ranges of total serum IgG subclass levels by Siemens Healthcare Diagnostics Inc. The values of the Kruskal–Wallis test followed by Dunn’s multiple comparisons test are presented in the vaccinated cohort. p < 0.05 was considered statistically significant.

    Article Snippet: Native human IgG2 protein , abcam , ab90284.

    Techniques: Enzyme-linked Immunosorbent Assay, Purification, Plasmid Preparation

    Heatmaps representing the log mean fold change values of spike-specific and total serum IgG subclasses in three follow-up mRNA vaccinated groups between two sampling time points after booster vaccination. The fold changes of spike-specific and total serum IgG subclasses and the proportions of each spike-specific to total serum IgG levels were visualized in heatmaps by the logarithmic values of mean ratios between the second and the first sampling time points. Decreasing trends are shown between 0 and (− 1) and increasing trends were plotted between 0 and 1. The constant level (no change) is indicated as 0.

    Journal: Scientific Reports

    Article Title: Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history

    doi: 10.1038/s41598-023-40103-x

    Figure Lengend Snippet: Heatmaps representing the log mean fold change values of spike-specific and total serum IgG subclasses in three follow-up mRNA vaccinated groups between two sampling time points after booster vaccination. The fold changes of spike-specific and total serum IgG subclasses and the proportions of each spike-specific to total serum IgG levels were visualized in heatmaps by the logarithmic values of mean ratios between the second and the first sampling time points. Decreasing trends are shown between 0 and (− 1) and increasing trends were plotted between 0 and 1. The constant level (no change) is indicated as 0.

    Article Snippet: Native human IgG2 protein , abcam , ab90284.

    Techniques: Sampling

    Contribution of each spike-specific IgG subclass to the sum of all spike-specific IgG antibody levels. The percentages of each spike-specific IgG subclass relative to the sum of spike-specific IgG levels are shown for the vaccinated and COVID-19 cohorts. The numbers represent the mean percentages of individuals calculated by dividing each spike specific IgG levels with the sum of all spike specific IgG levels. Schematic representation of spike-specific IgG1%, IgG2%, IgG3% and IgG4% are shown in blue, orange, grey and yellow sectors, respectively. The size of the pie charts indicates the levels of all spike-specific IgG antibodies from Fig. .

    Journal: Scientific Reports

    Article Title: Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history

    doi: 10.1038/s41598-023-40103-x

    Figure Lengend Snippet: Contribution of each spike-specific IgG subclass to the sum of all spike-specific IgG antibody levels. The percentages of each spike-specific IgG subclass relative to the sum of spike-specific IgG levels are shown for the vaccinated and COVID-19 cohorts. The numbers represent the mean percentages of individuals calculated by dividing each spike specific IgG levels with the sum of all spike specific IgG levels. Schematic representation of spike-specific IgG1%, IgG2%, IgG3% and IgG4% are shown in blue, orange, grey and yellow sectors, respectively. The size of the pie charts indicates the levels of all spike-specific IgG antibodies from Fig. .

    Article Snippet: Native human IgG2 protein , abcam , ab90284.

    Techniques:

    Key resources.

    Journal: Scientific Reports

    Article Title: Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history

    doi: 10.1038/s41598-023-40103-x

    Figure Lengend Snippet: Key resources.

    Article Snippet: Native human IgG2 protein , abcam , ab90284.

    Techniques: Recombinant, Software